pentobarbital will decrease the level or effect of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Bildskärm.lasmiditan, pentobarbital. Either increases effects of the other by sedation. Use Caution/Skärm. Coadministration of lasmiditan and other CNS depressant drugs, including alcohol have not been evaluated in